Isolation was also associated with inappropriate antibiotic therapy on the 1st and 4th days ( p = 0.011 and 0.032, respectively) but not with mortality on the 30th day.
Isolation of ESBL-producing strains was significantly associated with onset in a hospital ( p = 0.030), receiving hemodialysis ( p = 0.0050), and previous antibiotic use within 1 month ( p = 0.036 especially penicillin and/or cephalosporin ( p = 0.010) and fluoroquinolone ( p = 0.0069)). All ESBL-producing strains with the gene encoding the CTX-M-2-group were genetically nonidentical. mirabilis bacteremia identified in the Minami Ibaraki Area, Japan, between 20 and compared the characteristics of cases with ESBL-producing and ESBL-non-producing strains (13 and 51 cases, respectively). Although Proteus mirabilis is a common human pathogen, bacteremia caused by the organism, especially strains producing extended-spectrum beta-lactamase (ESBL), has rarely been investigated.
